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Resolution of structural variation in diverse mouse genomes reveals chromatin remodeling due to transposable elements

Diverse inbred mouse strains are important biomedical research models, yet genome characterization of many strains is fundamentally lacking in comparison with humans. In particular, catalogs of structural variants (SVs) (variants ≥ 50 bp) are incomplete, limiting the discovery of causative alleles f...

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Detalles Bibliográficos
Autores principales: Ferraj, Ardian, Audano, Peter A., Balachandran, Parithi, Czechanski, Anne, Flores, Jacob I., Radecki, Alexander A., Mosur, Varun, Gordon, David S., Walawalkar, Isha A., Eichler, Evan E., Reinholdt, Laura G., Beck, Christine R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203049/
https://www.ncbi.nlm.nih.gov/pubmed/37228752
http://dx.doi.org/10.1016/j.xgen.2023.100291