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Resolution of structural variation in diverse mouse genomes reveals chromatin remodeling due to transposable elements
Diverse inbred mouse strains are important biomedical research models, yet genome characterization of many strains is fundamentally lacking in comparison with humans. In particular, catalogs of structural variants (SVs) (variants ≥ 50 bp) are incomplete, limiting the discovery of causative alleles f...
Autores principales: | Ferraj, Ardian, Audano, Peter A., Balachandran, Parithi, Czechanski, Anne, Flores, Jacob I., Radecki, Alexander A., Mosur, Varun, Gordon, David S., Walawalkar, Isha A., Eichler, Evan E., Reinholdt, Laura G., Beck, Christine R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203049/ https://www.ncbi.nlm.nih.gov/pubmed/37228752 http://dx.doi.org/10.1016/j.xgen.2023.100291 |
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