Amplification is the primary mode of gene-by-sex interaction in complex human traits

Sex differences in complex traits are suspected to be in part due to widespread gene-by-sex interactions (GxSex), but empirical evidence has been elusive. Here, we infer the mixture of ways in which polygenic effects on physiological traits covary between males and females. We find that GxSex is per...

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Detalles Bibliográficos
Autores principales: Zhu, Carrie, Ming, Matthew J., Cole, Jared M., Edge, Michael D., Kirkpatrick, Mark, Harpak, Arbel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203050/
https://www.ncbi.nlm.nih.gov/pubmed/37228747
http://dx.doi.org/10.1016/j.xgen.2023.100297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203050/
https://www.ncbi.nlm.nih.gov/pubmed/37228747
http://dx.doi.org/10.1016/j.xgen.2023.100297

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