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Amplification is the primary mode of gene-by-sex interaction in complex human traits
Sex differences in complex traits are suspected to be in part due to widespread gene-by-sex interactions (GxSex), but empirical evidence has been elusive. Here, we infer the mixture of ways in which polygenic effects on physiological traits covary between males and females. We find that GxSex is per...
Autores principales: | Zhu, Carrie, Ming, Matthew J., Cole, Jared M., Edge, Michael D., Kirkpatrick, Mark, Harpak, Arbel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203050/ https://www.ncbi.nlm.nih.gov/pubmed/37228747 http://dx.doi.org/10.1016/j.xgen.2023.100297 |
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