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The association between dietary acrylamide intake and the risk of type 2 diabetes incidence in the Tehran lipid and glucose study

This study aimed at investigating the association of acrylamide consumption with the incidence of type 2 diabetes (T2D) in adults. The 6022 subjects of the Tehran lipid and glucose study participants were selected. The acrylamide content of food items were summed and computed cumulatively across fol...

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Autores principales: Hosseini-Esfahani, Firoozeh, Beheshti, Niloofar, Nematollahi, Amene, Koochakpoor, Glareh, verij-Kazemi, Soheil, Mirmiran, Parvin, Azizi, Fereidoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203125/
https://www.ncbi.nlm.nih.gov/pubmed/37217800
http://dx.doi.org/10.1038/s41598-023-35493-x
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author Hosseini-Esfahani, Firoozeh
Beheshti, Niloofar
Nematollahi, Amene
Koochakpoor, Glareh
verij-Kazemi, Soheil
Mirmiran, Parvin
Azizi, Fereidoon
author_facet Hosseini-Esfahani, Firoozeh
Beheshti, Niloofar
Nematollahi, Amene
Koochakpoor, Glareh
verij-Kazemi, Soheil
Mirmiran, Parvin
Azizi, Fereidoon
author_sort Hosseini-Esfahani, Firoozeh
collection PubMed
description This study aimed at investigating the association of acrylamide consumption with the incidence of type 2 diabetes (T2D) in adults. The 6022 subjects of the Tehran lipid and glucose study participants were selected. The acrylamide content of food items were summed and computed cumulatively across follow up surveys. Multivariable Cox proportional hazard regression analyses were performed to estimate the hazards ratio (HR) and 95% confidence interval (CI) of incident T2D. This study was done on men and women, respectively aged 41.5 ± 14.1 and 39.2 ± 13.0 years. The mean ± SD of dietary acrylamide intake was 57.0 ± 46.8 µg/day. Acrylamide intake was not associated with the incidence of T2D after adjusting for confounding variables. In women, a higher acrylamide intake was positively associated with T2D [HR (CI) for Q4: 1.13 (1.01–1.27), P trend: 0.03] after adjusting for confounding factors. Our results demonstrated that dietary intake of acrylamide was associated with an increased risk of T2D in women.
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spelling pubmed-102031252023-05-24 The association between dietary acrylamide intake and the risk of type 2 diabetes incidence in the Tehran lipid and glucose study Hosseini-Esfahani, Firoozeh Beheshti, Niloofar Nematollahi, Amene Koochakpoor, Glareh verij-Kazemi, Soheil Mirmiran, Parvin Azizi, Fereidoon Sci Rep Article This study aimed at investigating the association of acrylamide consumption with the incidence of type 2 diabetes (T2D) in adults. The 6022 subjects of the Tehran lipid and glucose study participants were selected. The acrylamide content of food items were summed and computed cumulatively across follow up surveys. Multivariable Cox proportional hazard regression analyses were performed to estimate the hazards ratio (HR) and 95% confidence interval (CI) of incident T2D. This study was done on men and women, respectively aged 41.5 ± 14.1 and 39.2 ± 13.0 years. The mean ± SD of dietary acrylamide intake was 57.0 ± 46.8 µg/day. Acrylamide intake was not associated with the incidence of T2D after adjusting for confounding variables. In women, a higher acrylamide intake was positively associated with T2D [HR (CI) for Q4: 1.13 (1.01–1.27), P trend: 0.03] after adjusting for confounding factors. Our results demonstrated that dietary intake of acrylamide was associated with an increased risk of T2D in women. Nature Publishing Group UK 2023-05-22 /pmc/articles/PMC10203125/ /pubmed/37217800 http://dx.doi.org/10.1038/s41598-023-35493-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Hosseini-Esfahani, Firoozeh
Beheshti, Niloofar
Nematollahi, Amene
Koochakpoor, Glareh
verij-Kazemi, Soheil
Mirmiran, Parvin
Azizi, Fereidoon
The association between dietary acrylamide intake and the risk of type 2 diabetes incidence in the Tehran lipid and glucose study
title The association between dietary acrylamide intake and the risk of type 2 diabetes incidence in the Tehran lipid and glucose study
title_full The association between dietary acrylamide intake and the risk of type 2 diabetes incidence in the Tehran lipid and glucose study
title_fullStr The association between dietary acrylamide intake and the risk of type 2 diabetes incidence in the Tehran lipid and glucose study
title_full_unstemmed The association between dietary acrylamide intake and the risk of type 2 diabetes incidence in the Tehran lipid and glucose study
title_short The association between dietary acrylamide intake and the risk of type 2 diabetes incidence in the Tehran lipid and glucose study
title_sort association between dietary acrylamide intake and the risk of type 2 diabetes incidence in the tehran lipid and glucose study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203125/
https://www.ncbi.nlm.nih.gov/pubmed/37217800
http://dx.doi.org/10.1038/s41598-023-35493-x
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