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Allnighter pseudokinase-mediated feedback links proteostasis and sleep in Drosophila

In nervous systems, retrograde signals are key for organizing circuit activity and maintaining neuronal homeostasis. We identify the conserved Allnighter (Aln) pseudokinase as a cell non-autonomous regulator of proteostasis responses necessary for normal sleep and structural plasticity of Drosophila...

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Detalles Bibliográficos
Autores principales: Shekhar, Shashank, Moehlman, Andrew T., Park, Brenden, Ewnetu, Michael, Tracy, Charles, Titos, Iris, Pawłowski, Krzysztof, Tagliabracci, Vincent S., Krämer, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203134/
https://www.ncbi.nlm.nih.gov/pubmed/37217484
http://dx.doi.org/10.1038/s41467-023-38485-7