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LncRNA FAS-AS1 upregulated by its genetic variation rs6586163 promotes cell apoptosis in nasopharyngeal carcinoma through regulating mitochondria function and Fas splicing

Nasopharyngeal carcinoma (NPC) is a common head and neck malignant with a high incidence in Southern China. Genetic aberrations play a vital role in the pathogenesis, progression and prognosis of NPC. In the present study, we elucidated the underlying mechanism of FAS-AS1 and its genetic variation r...

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Detalles Bibliográficos
Autores principales: Guo, Zhen, Li, ZiBo, Zhang, MengLing, Bao, MeiHua, He, BinSheng, Zhou, XiaoLong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203136/
https://www.ncbi.nlm.nih.gov/pubmed/37217794
http://dx.doi.org/10.1038/s41598-023-35502-z