Engineered bacterial outer membrane vesicles encapsulating oncolytic adenoviruses enhance the efficacy of cancer virotherapy by augmenting tumor cell autophagy

Oncolytic adenovirus (Ad) infection promotes intracellular autophagy in tumors. This could kill cancer cells and contribute to Ads-mediated anticancer immunity. However, the low intratumoral content of intravenously delivered Ads could be insufficient to efficiently activate tumor over-autophagy. He...

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Detalles Bibliográficos
Autores principales: Ban, Weiyue, Sun, Mengchi, Huang, Hanwei, Huang, Wanxu, Pan, Siwei, Liu, Pengfei, Li, Bingwu, Cheng, Zhenguo, He, Zhonggui, Liu, Funan, Sun, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203215/
https://www.ncbi.nlm.nih.gov/pubmed/37217527
http://dx.doi.org/10.1038/s41467-023-38679-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203215/
https://www.ncbi.nlm.nih.gov/pubmed/37217527
http://dx.doi.org/10.1038/s41467-023-38679-z

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