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Assessment of the physicochemical and sensory characteristics of fermented camel milk fortified with Cordia myxa and its biological effects against oxidative stress and hyperlipidemia in rats

Natural feed additives and their potential benefits in production of safe and highly nutritious food have gained the attention of many researchers the last decades. Cordia myxa is a nutrient-dense food with various health benefits. Despite this fact, very limited studied investigated the physicochem...

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Autores principales: Atwaa, El Sayed Hassan, Shahein, Magdy Ramadan, Raya-Álvarez, Enrique, Abd El-Sattar, El Sayed, Hassan, Moustafa A. A., Hashim, Madeha Ahmed, Dahran, Naief, El-Khadragy, Manal F., Agil, Ahmad, Elmahallawy, Ehab Kotb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203225/
https://www.ncbi.nlm.nih.gov/pubmed/37229477
http://dx.doi.org/10.3389/fnut.2023.1130224
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author Atwaa, El Sayed Hassan
Shahein, Magdy Ramadan
Raya-Álvarez, Enrique
Abd El-Sattar, El Sayed
Hassan, Moustafa A. A.
Hashim, Madeha Ahmed
Dahran, Naief
El-Khadragy, Manal F.
Agil, Ahmad
Elmahallawy, Ehab Kotb
author_facet Atwaa, El Sayed Hassan
Shahein, Magdy Ramadan
Raya-Álvarez, Enrique
Abd El-Sattar, El Sayed
Hassan, Moustafa A. A.
Hashim, Madeha Ahmed
Dahran, Naief
El-Khadragy, Manal F.
Agil, Ahmad
Elmahallawy, Ehab Kotb
author_sort Atwaa, El Sayed Hassan
collection PubMed
description Natural feed additives and their potential benefits in production of safe and highly nutritious food have gained the attention of many researchers the last decades. Cordia myxa is a nutrient-dense food with various health benefits. Despite this fact, very limited studied investigated the physicochemical and sensory impacts of incorporation of fermented camel milk with Cordia myxa and its biological effects. The current study aimed to assess the physical, chemical, and sensory characteristics of fermented camel milk (FCM) fortified with 5, 10, and 15% Cordia myxa pulp. The study demonstrated that fortification of camel milk efficiently enhanced protein, total solids, ash, fiber, phenolic substance, and antioxidant activity. When compared to other treatments, FCM supplemented with 10% Cordia myxa pulp had the best sensory features. In addition, FCM fortified with 10% Cordia myxa pulp was investigated as a potential inhibitor of hypercholesterolemia agents in obese rats. Thirty-two male Wistar rats were split into two main groups including normal pellet group (n = 8) served as negative control group (G1) and a group of hyperlipidemic animals (n = 24) were feed on a high-fat diet (HFD). Hyperlipidemic rats group (n = 24) were then divided into three subgroups (8 per each); second group or positive control (G2) which include hyperlipidemic rats received distilled water (1 mL/day), the third group (G3) involved hyperlipidemic rats feed on FCM (10 g/day) and the fourth group (G4) included hyperlipidemic animals feed on 10 g/day FCM fortified with 10% of Cordia myxa pulp by oral treatment via an intestinal tube for another 4 weeks. In contrast to the positive control group, G4 treated with Cordia myxa showed a substantial decrease in malondialdehyde, LDL, cholesterol, triglycerides, AST, ALT, creatinine, and urea levels, while a significant increase in HDL, albumin, and total protein concentrations. The number of large adipocytes decreased while the number of small adipocytes increased after consumption of fortified FCM. The results indicated that fermented milk fortified with Cordia myxa pulp improved the functions of the liver and kidney in hyperlipidemic rats. These results demonstrated the protective effects of camel milk and Cordia myxa pulp against hyperlipidemia in rats.
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spelling pubmed-102032252023-05-24 Assessment of the physicochemical and sensory characteristics of fermented camel milk fortified with Cordia myxa and its biological effects against oxidative stress and hyperlipidemia in rats Atwaa, El Sayed Hassan Shahein, Magdy Ramadan Raya-Álvarez, Enrique Abd El-Sattar, El Sayed Hassan, Moustafa A. A. Hashim, Madeha Ahmed Dahran, Naief El-Khadragy, Manal F. Agil, Ahmad Elmahallawy, Ehab Kotb Front Nutr Nutrition Natural feed additives and their potential benefits in production of safe and highly nutritious food have gained the attention of many researchers the last decades. Cordia myxa is a nutrient-dense food with various health benefits. Despite this fact, very limited studied investigated the physicochemical and sensory impacts of incorporation of fermented camel milk with Cordia myxa and its biological effects. The current study aimed to assess the physical, chemical, and sensory characteristics of fermented camel milk (FCM) fortified with 5, 10, and 15% Cordia myxa pulp. The study demonstrated that fortification of camel milk efficiently enhanced protein, total solids, ash, fiber, phenolic substance, and antioxidant activity. When compared to other treatments, FCM supplemented with 10% Cordia myxa pulp had the best sensory features. In addition, FCM fortified with 10% Cordia myxa pulp was investigated as a potential inhibitor of hypercholesterolemia agents in obese rats. Thirty-two male Wistar rats were split into two main groups including normal pellet group (n = 8) served as negative control group (G1) and a group of hyperlipidemic animals (n = 24) were feed on a high-fat diet (HFD). Hyperlipidemic rats group (n = 24) were then divided into three subgroups (8 per each); second group or positive control (G2) which include hyperlipidemic rats received distilled water (1 mL/day), the third group (G3) involved hyperlipidemic rats feed on FCM (10 g/day) and the fourth group (G4) included hyperlipidemic animals feed on 10 g/day FCM fortified with 10% of Cordia myxa pulp by oral treatment via an intestinal tube for another 4 weeks. In contrast to the positive control group, G4 treated with Cordia myxa showed a substantial decrease in malondialdehyde, LDL, cholesterol, triglycerides, AST, ALT, creatinine, and urea levels, while a significant increase in HDL, albumin, and total protein concentrations. The number of large adipocytes decreased while the number of small adipocytes increased after consumption of fortified FCM. The results indicated that fermented milk fortified with Cordia myxa pulp improved the functions of the liver and kidney in hyperlipidemic rats. These results demonstrated the protective effects of camel milk and Cordia myxa pulp against hyperlipidemia in rats. Frontiers Media S.A. 2023-05-09 /pmc/articles/PMC10203225/ /pubmed/37229477 http://dx.doi.org/10.3389/fnut.2023.1130224 Text en Copyright © 2023 Atwaa, Shahein, Raya-Álvarez, Abd El-Sattar, Hassan, Hashim, Dahran, El-Khadragy, Agil and Elmahallawy. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Atwaa, El Sayed Hassan
Shahein, Magdy Ramadan
Raya-Álvarez, Enrique
Abd El-Sattar, El Sayed
Hassan, Moustafa A. A.
Hashim, Madeha Ahmed
Dahran, Naief
El-Khadragy, Manal F.
Agil, Ahmad
Elmahallawy, Ehab Kotb
Assessment of the physicochemical and sensory characteristics of fermented camel milk fortified with Cordia myxa and its biological effects against oxidative stress and hyperlipidemia in rats
title Assessment of the physicochemical and sensory characteristics of fermented camel milk fortified with Cordia myxa and its biological effects against oxidative stress and hyperlipidemia in rats
title_full Assessment of the physicochemical and sensory characteristics of fermented camel milk fortified with Cordia myxa and its biological effects against oxidative stress and hyperlipidemia in rats
title_fullStr Assessment of the physicochemical and sensory characteristics of fermented camel milk fortified with Cordia myxa and its biological effects against oxidative stress and hyperlipidemia in rats
title_full_unstemmed Assessment of the physicochemical and sensory characteristics of fermented camel milk fortified with Cordia myxa and its biological effects against oxidative stress and hyperlipidemia in rats
title_short Assessment of the physicochemical and sensory characteristics of fermented camel milk fortified with Cordia myxa and its biological effects against oxidative stress and hyperlipidemia in rats
title_sort assessment of the physicochemical and sensory characteristics of fermented camel milk fortified with cordia myxa and its biological effects against oxidative stress and hyperlipidemia in rats
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203225/
https://www.ncbi.nlm.nih.gov/pubmed/37229477
http://dx.doi.org/10.3389/fnut.2023.1130224
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