Structural analysis of an endogenous 4-megadalton succinyl-CoA-generating metabolon

The oxoglutarate dehydrogenase complex (OGDHc) participates in the tricarboxylic acid cycle and, in a multi-step reaction, decarboxylates α-ketoglutarate, transfers succinyl to CoA, and reduces NAD+. Due to its pivotal role in metabolism, OGDHc enzymatic components have been studied in isolation; ho...

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Detalles Bibliográficos
Autores principales: Skalidis, Ioannis, Kyrilis, Fotis L., Tüting, Christian, Hamdi, Farzad, Träger, Toni K., Belapure, Jaydeep, Hause, Gerd, Fratini, Marta, O’Reilly, Francis J., Heilmann, Ingo, Rappsilber, Juri, Kastritis, Panagiotis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203282/
https://www.ncbi.nlm.nih.gov/pubmed/37217784
http://dx.doi.org/10.1038/s42003-023-04885-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203282/
https://www.ncbi.nlm.nih.gov/pubmed/37217784
http://dx.doi.org/10.1038/s42003-023-04885-0

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