Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models

Cellular senescence is known to play a role in age-related skin function deterioration which potentially influences longevity. Here, a two-step phenotypic screening was performed to identify senotherapeutic peptides, leading to the identification of Peptide (Pep) 14. Pep 14 effectively decreased hum...

Descripción completa

Detalles Bibliográficos
Autores principales: Zonari, Alessandra, Brace, Lear E., Al-Katib, Kallie, Porto, William F., Foyt, Daniel, Guiang, Mylieneth, Cruz, Edgar Andres Ochoa, Marshall, Bailey, Gentz, Melissa, Guimarães, Gabriela Rapozo, Franco, Octavio L., Oliveira, Carolina R., Boroni, Mariana, Carvalho, Juliana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203313/
https://www.ncbi.nlm.nih.gov/pubmed/37217561
http://dx.doi.org/10.1038/s41514-023-00109-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203313/
https://www.ncbi.nlm.nih.gov/pubmed/37217561
http://dx.doi.org/10.1038/s41514-023-00109-1

Ejemplares similares