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Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models
Cellular senescence is known to play a role in age-related skin function deterioration which potentially influences longevity. Here, a two-step phenotypic screening was performed to identify senotherapeutic peptides, leading to the identification of Peptide (Pep) 14. Pep 14 effectively decreased hum...
Autores principales: | Zonari, Alessandra, Brace, Lear E., Al-Katib, Kallie, Porto, William F., Foyt, Daniel, Guiang, Mylieneth, Cruz, Edgar Andres Ochoa, Marshall, Bailey, Gentz, Melissa, Guimarães, Gabriela Rapozo, Franco, Octavio L., Oliveira, Carolina R., Boroni, Mariana, Carvalho, Juliana L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203313/ https://www.ncbi.nlm.nih.gov/pubmed/37217561 http://dx.doi.org/10.1038/s41514-023-00109-1 |
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