Cargando…

Dasatinib overcomes glucocorticoid resistance in B-cell acute lymphoblastic leukemia

Resistance to glucocorticoids (GC) is associated with an increased risk of relapse in B-cell progenitor acute lymphoblastic leukemia (BCP-ALL). Performing transcriptomic and single-cell proteomic studies in healthy B-cell progenitors, we herein identify coordination between the glucocorticoid recept...

Descripción completa

Detalles Bibliográficos
Autores principales: Sarno, Jolanda, Domizi, Pablo, Liu, Yuxuan, Merchant, Milton, Pedersen, Christina Bligaard, Jedoui, Dorra, Jager, Astraea, Nolan, Garry P., Gaipa, Giuseppe, Bendall, Sean C., Bava, Felice-Alessio, Davis, Kara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203345/
https://www.ncbi.nlm.nih.gov/pubmed/37217509
http://dx.doi.org/10.1038/s41467-023-38456-y