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Dasatinib overcomes glucocorticoid resistance in B-cell acute lymphoblastic leukemia
Resistance to glucocorticoids (GC) is associated with an increased risk of relapse in B-cell progenitor acute lymphoblastic leukemia (BCP-ALL). Performing transcriptomic and single-cell proteomic studies in healthy B-cell progenitors, we herein identify coordination between the glucocorticoid recept...
Autores principales: | Sarno, Jolanda, Domizi, Pablo, Liu, Yuxuan, Merchant, Milton, Pedersen, Christina Bligaard, Jedoui, Dorra, Jager, Astraea, Nolan, Garry P., Gaipa, Giuseppe, Bendall, Sean C., Bava, Felice-Alessio, Davis, Kara L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203345/ https://www.ncbi.nlm.nih.gov/pubmed/37217509 http://dx.doi.org/10.1038/s41467-023-38456-y |
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