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Intestine and brain TLR-4 modulation following N-acetyl-cysteine treatment in NEC rodent model

Necrotizing enterocolitis (NEC) brain injury is mediated through Toll-like receptor 4 (TLR4) on the intestinal epithelium and brain microglia. Our aim was to determine whether postnatal and/or prenatal NAC can modify NEC associated intestinal and brain TLR4 expression and brain glutathione levels in...

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Detalles Bibliográficos
Autores principales: Beloosesky, Ron, Gutzeit, Ola, Ginsberg, Yuval, Khatib, Nizar, Ross, Michael G., Weiner, Zeev, Zmora, Osnat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203358/
https://www.ncbi.nlm.nih.gov/pubmed/37217588
http://dx.doi.org/10.1038/s41598-023-35019-5