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MEP pathway products allosterically promote monomerization of deoxy-D-xylulose-5-phosphate synthase to feedback-regulate their supply

Isoprenoids are a very large and diverse family of metabolites required by all living organisms. All isoprenoids derive from the double-bond isomers isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), which are produced by the methylerythritol 4-phosphate (MEP) pathway in bacteria a...

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Detalles Bibliográficos
Autores principales: Di, Xueni, Ortega-Alarcon, David, Kakumanu, Ramu, Iglesias-Fernandez, Javier, Diaz, Lucia, Baidoo, Edward E.K., Velazquez-Campoy, Adrian, Rodríguez-Concepción, Manuel, Perez-Gil, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203381/
https://www.ncbi.nlm.nih.gov/pubmed/36575800
http://dx.doi.org/10.1016/j.xplc.2022.100512