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Functional single nucleotide polymorphisms in dopaminergic receptors D2 predict clinical response to Cariprazine

Cariprazine (CAR) is an antipsychotic drug for the treatment of schizophrenia (SCZ) and bipolar disorder (BD), and it acts as a partial agonist on the dopamine receptors (DR), D2, and D3. Although many single nucleotide polymorphisms (SNPs) in genes coding for these receptors are known to influence...

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Detalles Bibliográficos
Autores principales: De Pieri, Marco, Ferrari, Marco, Marino, Franca, Traber, Rafael, Bolla, Emilio, Cosentino, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203397/
https://www.ncbi.nlm.nih.gov/pubmed/37229261
http://dx.doi.org/10.3389/fphar.2023.1182393