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Evaluating efficacy and safety of sub-anesthetic dose esketamine as an adjuvant to propofol/remifentanil analgosedation and spontaneous respiration for children flexible fibreoptic bronchoscopy: a prospective, double-blinded, randomized, and placebo-controlled clinical trial

Background: Flexible fiberoptic bronchoscopy (FFB) for children is widely performed under sedation. Currently, the optimal sedation regimen remains unclear. Esketamine is an N-methyl-D-aspartic acid (NMDA) receptor antagonist, which has stronger sedative and analgesic effects and exerts less cardior...

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Detalles Bibliográficos
Autores principales: Zhong, Yu, Jiang, Min, Wang, Yunshi, Su, Tingting, Lv, Yuanzhi, Fan, Zhiqing, Ning, Hengyi, Yang, Yilan, Chen, Yanhua, Xie, Yubo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203403/
https://www.ncbi.nlm.nih.gov/pubmed/37229247
http://dx.doi.org/10.3389/fphar.2023.1184663