African swine fever virus QP383R dampens type I interferon production by promoting cGAS palmitoylation

Cyclic GMP-AMP synthase (cGAS) recognizes viral DNA and synthesizes cyclic GMP-AMP (cGAMP), which activates stimulator of interferon genes (STING/MITA) and downstream mediators to elicit an innate immune response. African swine fever virus (ASFV) proteins can antagonize host immune responses to prom...

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Detalles Bibliográficos
Autores principales: Hao, Siyuan, Zheng, Xiaojie, Zhu, Yingqi, Yao, Yao, Li, Sihan, Xu, Yangyang, Feng, Wen-hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203406/
https://www.ncbi.nlm.nih.gov/pubmed/37228597
http://dx.doi.org/10.3389/fimmu.2023.1186916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203406/
https://www.ncbi.nlm.nih.gov/pubmed/37228597
http://dx.doi.org/10.3389/fimmu.2023.1186916

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