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Human IL-32θA94V mutant attenuates monocyte-endothelial adhesion by suppressing the expression of ICAM-1 and VCAM-1 via binding to cell surface receptor integrin αVβ3 and αVβ6 in TNF-α-stimulated HUVECs

Interleukin-32 (IL-32), first reported in 2005, and its isoforms have been the subject of numerous studies investigating their functions in virus infection, cancer, and inflammation. IL-32θ, one of the IL-32 isoforms, has been shown to modulate cancer development and inflammatory responses. A recent...

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Detalles Bibliográficos
Autores principales: Park, Jae-Young, Park, Hyo-Min, Kim, Seonhwa, Jeon, Kyeong-Bae, Lim, Chae-Min, Hong, Jin Tae, Yoon, Do-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203490/
https://www.ncbi.nlm.nih.gov/pubmed/37228610
http://dx.doi.org/10.3389/fimmu.2023.1160301