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Biological activity of human IgE monoclonal antibodies targeting Der p 2, Fel d 1, Ara h 2 in basophil mediator release assays

BACKGROUND: Human Immunoglobulin E monoclonal antibodies (hIgE mAb) are unique tools for investigating IgE responses. Here, the biological activity of hIgE mAb, derived from immortalized B cells harvested from the blood of allergic donors, targeting three allergens (Der p 2, Fel d 1 and Ara h 2) was...

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Detalles Bibliográficos
Autores principales: Pena-Castellanos, Glorismer, Smith, Bryan R. E., Pomés, Anna, Smith, Scott A., Stigler, Maria A., Widauer, Hannah L., Versteeg, Serge A., van Ree, Ronald, Chapman, Martin D., Aglas, Lorenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203493/
https://www.ncbi.nlm.nih.gov/pubmed/37228609
http://dx.doi.org/10.3389/fimmu.2023.1155613