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Overexpression of IκB⍺ modulates NF-κB activation of inflammatory target gene expression

Cells respond to inflammatory stimuli such as cytokines by activation of the nuclear factor-κB (NF-κB) signalling pathway, resulting in oscillatory translocation of the transcription factor p65 between nucleus and cytoplasm in some cell types. We investigate the relationship between p65 and inhibito...

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Detalles Bibliográficos
Autores principales: Downton, Polly, Bagnall, James S., England, Hazel, Spiller, David G., Humphreys, Neil E., Jackson, Dean A., Paszek, Pawel, White, Michael R. H., Adamson, Antony D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203502/
https://www.ncbi.nlm.nih.gov/pubmed/37228587
http://dx.doi.org/10.3389/fmolb.2023.1187187