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Identification of afatinib-associated ADH1B and potential small-molecule drugs targeting ADH1B for hepatocellular carcinoma

Background: Afatinib is an irreversible epidermal growth factor receptor tyrosine kinase inhibitor, and it plays a role in hepatocellular carcinoma (LIHC). This study aimed to screen a key gene associated with afatinib and identify its potential candidate drugs. Methods: We screened afatinib-associa...

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Detalles Bibliográficos
Autores principales: Zhou, Yongxu, Yu, Liang, Huang, Peng, Zhao, Xudong, He, Risheng, Cui, Yunfu, Pan, Bo, Liu, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203513/
https://www.ncbi.nlm.nih.gov/pubmed/37229243
http://dx.doi.org/10.3389/fphar.2023.1166454