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Identification of afatinib-associated ADH1B and potential small-molecule drugs targeting ADH1B for hepatocellular carcinoma
Background: Afatinib is an irreversible epidermal growth factor receptor tyrosine kinase inhibitor, and it plays a role in hepatocellular carcinoma (LIHC). This study aimed to screen a key gene associated with afatinib and identify its potential candidate drugs. Methods: We screened afatinib-associa...
Autores principales: | Zhou, Yongxu, Yu, Liang, Huang, Peng, Zhao, Xudong, He, Risheng, Cui, Yunfu, Pan, Bo, Liu, Chang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203513/ https://www.ncbi.nlm.nih.gov/pubmed/37229243 http://dx.doi.org/10.3389/fphar.2023.1166454 |
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