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Establishment, characterization, and drug screening of low-passage patient individual non-small cell lung cancer in vitro models including the rare pleomorphic subentity

INTRODUCTION: For pre-clinical drug development and precision oncology research, robust cancer cell models are essential. Patient-derived models in low passages retain more genetic and phenotypic characteristics of their original tumors than conventional cancer cell lines. Subentity, individual gene...

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Detalles Bibliográficos
Autores principales: Andus, Ingo, Prall, Friedrich, Linnebacher, Michael, Linnebacher, Christina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203569/
https://www.ncbi.nlm.nih.gov/pubmed/37228492
http://dx.doi.org/10.3389/fonc.2023.1089681