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A rapid and efficient platform for antiviral crRNA screening using CRISPR-Cas13a-based nucleic acid detection

INTRODUCTION: Rapid and high-throughput screening of antiviral clustered regularly interspaced short palindromic repeat (CRISPR) RNAs (crRNAs) is urgently required for the CRISPR-Cas13a antiviral system. Based on the same principle, we established an efficient screening platform for antiviral crRNA...

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Detalles Bibliográficos
Autores principales: Yang, Lan, Zhang, Youcui, Yi, Wenyanbo, Dong, Xue, Niu, Mengwei, Song, Yingjie, Han, Yao, Li, Hao, Sun, Yansong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203571/
https://www.ncbi.nlm.nih.gov/pubmed/37228594
http://dx.doi.org/10.3389/fimmu.2023.1116230