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Investigation of heteroscedasticity in polygenic risk scores across 15 quantitative traits
The polygenic risk score (PRS) could be used to stratify individuals with high risk of diseases and predict complex trait of individual in a population. Previous studies developed a PRS-based prediction model using linear regression and evaluated the predictive performance of the model using the R (...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203621/ https://www.ncbi.nlm.nih.gov/pubmed/37229196 http://dx.doi.org/10.3389/fgene.2023.1150889 |