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Investigation of heteroscedasticity in polygenic risk scores across 15 quantitative traits

The polygenic risk score (PRS) could be used to stratify individuals with high risk of diseases and predict complex trait of individual in a population. Previous studies developed a PRS-based prediction model using linear regression and evaluated the predictive performance of the model using the R (...

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Detalles Bibliográficos
Autores principales: Jung, Hyein, Jung, Hae-Un, Baek, Eun Ju, Chung, Ju Yeon, Kwon, Shin Young, Kang, Ji-One, Lim, Ji Eun, Oh, Bermseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203621/
https://www.ncbi.nlm.nih.gov/pubmed/37229196
http://dx.doi.org/10.3389/fgene.2023.1150889