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Magnesium increases numbers of Foxp3+ Treg cells and reduces arthritis severity and joint damage in an IL-10-dependent manner mediated by the intestinal microbiome

BACKGROUND: Rheumatoid arthritis (RA) is a common autoimmune disease with emerging environmental and microbiome risk factors. The western diet is typically deficient in magnesium (Mg), and there is some evidence suggesting that Mg may have anti-inflammatory properties. But the actual role of Mg supp...

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Detalles Bibliográficos
Autores principales: Laragione, Teresina, Harris, Carolyn, Azizgolshani, Nasim, Beeton, Christine, Bongers, Gerold, Gulko, Percio S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203746/
https://www.ncbi.nlm.nih.gov/pubmed/37201335
http://dx.doi.org/10.1016/j.ebiom.2023.104603