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RAD51–WSS1-dependent genetic pathways are essential for DNA–protein crosslink repair and pathogenesis in Candida albicans

Genetic analyses in Saccharomyces cerevisiae suggest that nucleotide excision repair (NER), homologous recombination (HR), and protease-dependent repair pathways coordinately function to remove DNA–protein crosslinks (DPCs) from the genome. DPCs are genomic cytotoxic lesions generated because of the...

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Detalles Bibliográficos
Autores principales: Kumari, Premlata, Sahu, Satya Ranjan, Utkalaja, Bhabasha Gyanadeep, Dutta, Abinash, Acharya, Narottam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203778/
https://www.ncbi.nlm.nih.gov/pubmed/37080389
http://dx.doi.org/10.1016/j.jbc.2023.104728