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Design, physicochemical characterisation, and in vitro cytotoxicity of cisplatin-loaded PEGylated chitosan injectable nano / sub-micron crystals

The study aimed to develop cisplatin-loaded PEGylated chitosan nanoparticles. The optimal batch of cisplatin-loaded PEGylated chitosan nanoparticles had a + 49.9 mV zeta potential, PDI of 0.347, and % PDI of 58.9. Nanoparticle zeta size was 741.4 z. d.nm, the size in diameter was 866.7 ± 470.5 nm, a...

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Detalles Bibliográficos
Autores principales: Sultan, Muhammad H., Moni, Sivakumar S., Alqahtani, Saad S., Ali Bakkari, Mohammed, Alshammari, Abdulrahman, Almoshari, Yosif, Alshahrani, Saeed, Madkhali, Osama A., Mohan, Syam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203781/
https://www.ncbi.nlm.nih.gov/pubmed/37228326
http://dx.doi.org/10.1016/j.jsps.2023.04.005