On QSAR-based cardiotoxicity modeling with the expressiveness-enhanced graph learning model and dual-threshold scheme

Introduction: Given the direct association with malignant ventricular arrhythmias, cardiotoxicity is a major concern in drug design. In the past decades, computational models based on the quantitative structure–activity relationship have been proposed to screen out cardiotoxic compounds and have sho...

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Detalles Bibliográficos
Autores principales: Wang, Huijia, Zhu, Guangxian, Izu, Leighton T., Chen-Izu, Ye, Ono, Naoaki, Altaf-Ul-Amin, MD, Kanaya, Shigehiko, Huang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203956/
https://www.ncbi.nlm.nih.gov/pubmed/37228825
http://dx.doi.org/10.3389/fphys.2023.1156286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203956/
https://www.ncbi.nlm.nih.gov/pubmed/37228825
http://dx.doi.org/10.3389/fphys.2023.1156286

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