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A linear B-cell epitope close to the furin cleavage site within the S1 domain of SARS-CoV-2 Spike protein discriminates the humoral immune response of nucleic acid- and protein-based vaccine cohorts

BACKGROUND: Understanding the humoral immune response towards viral infection and vaccination is instrumental in developing therapeutic tools to fight and restrict the viral spread of global pandemics. Of particular interest are the specificity and breadth of antibody reactivity in order to pinpoint...

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Detalles Bibliográficos
Autores principales: Lorenz, Peter, Steinbeck, Felix, Mai, Franz, Reisinger, Emil C., Müller-Hilke, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203960/
https://www.ncbi.nlm.nih.gov/pubmed/37228598
http://dx.doi.org/10.3389/fimmu.2023.1192395