Renin-angiotensin system inhibitors mitigate radiation pneumonitis by activating ACE2-angiotensin-(1–7) axis via NF-κB/MAPK pathway

Radiation pneumonitis (RP) affects both patients and physicians during radiation therapy for lung cancer. To date, there are no effective drugs for improving the clinical outcomes of RP. The activation of angiotensin-converting enzyme 2 (ACE2) improves experimental acute lung injury caused by severe...

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Detalles Bibliográficos
Autores principales: Cong, Changsheng, Niu, Shiying, Jiang, Yifan, Zhang, Xinhui, Jing, Wang, Zheng, Yawen, Zhang, Xiaoyue, Su, Guohai, Zhang, Yueying, Sun, Meili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204016/
https://www.ncbi.nlm.nih.gov/pubmed/37221286
http://dx.doi.org/10.1038/s41598-023-35412-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204016/
https://www.ncbi.nlm.nih.gov/pubmed/37221286
http://dx.doi.org/10.1038/s41598-023-35412-0

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