Synthesis of a Complex Brasilicardin Analogue Utilizing a Cobalt-Catalyzed MHAT-Induced Radical Bicyclization Reaction

[Image: see text] We designed and executed an expedient synthesis of a complex analogue of the potent immunosuppressive natural product brasilicardin A. Our successful synthesis featured application of our recently developed MHAT-initiated radical bicyclization, which delivered the targeted, complex...

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Detalles Bibliográficos
Autores principales: Niman, Scott W., Buono, Roberta, Fruman, David A., Vanderwal, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204089/
https://www.ncbi.nlm.nih.gov/pubmed/37141632
http://dx.doi.org/10.1021/acs.orglett.3c01019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204089/
https://www.ncbi.nlm.nih.gov/pubmed/37141632
http://dx.doi.org/10.1021/acs.orglett.3c01019

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