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Synthesis of a Complex Brasilicardin Analogue Utilizing a Cobalt-Catalyzed MHAT-Induced Radical Bicyclization Reaction
[Image: see text] We designed and executed an expedient synthesis of a complex analogue of the potent immunosuppressive natural product brasilicardin A. Our successful synthesis featured application of our recently developed MHAT-initiated radical bicyclization, which delivered the targeted, complex...
Autores principales: | Niman, Scott W., Buono, Roberta, Fruman, David A., Vanderwal, Christopher D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204089/ https://www.ncbi.nlm.nih.gov/pubmed/37141632 http://dx.doi.org/10.1021/acs.orglett.3c01019 |
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