Visible Light Photoredox-Catalyzed Decarboxylative Alkylation of 3-Aryl-Oxetanes and Azetidines via Benzylic Tertiary Radicals and Implications of Benzylic Radical Stability

[Image: see text] Four-membered heterocycles offer exciting potential as small polar motifs in medicinal chemistry but require further methods for incorporation. Photoredox catalysis is a powerful method for the mild generation of alkyl radicals for C–C bond formation. The effect of ring strain on r...

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Detalles Bibliográficos
Autores principales: Dubois, Maryne A. J., Rojas, Juan J., Sterling, Alistair J., Broderick, Hannah C., Smith, Milo A., White, Andrew J. P., Miller, Philip W., Choi, Chulho, Mousseau, James J., Duarte, Fernanda, Bull, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204094/
https://www.ncbi.nlm.nih.gov/pubmed/36868184
http://dx.doi.org/10.1021/acs.joc.3c00083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204094/
https://www.ncbi.nlm.nih.gov/pubmed/36868184
http://dx.doi.org/10.1021/acs.joc.3c00083

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