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Associations between circulating cell-free mitochondrial DNA, inflammatory markers, and cognitive and physical outcomes in community dwelling older adults

BACKGROUND: Dementia and frailty are common age-related syndromes often linked to chronic inflammation. Identifying the biological factors and pathways that contribute to chronic inflammation is crucial for developing new therapeutic targets. Circulating cell-free mitochondrial DNA (ccf-mtDNA) has b...

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Detalles Bibliográficos
Autores principales: Nidadavolu, Lolita S., Feger, Danielle, Chen, Diefei, Wu, Yuqiong, Grodstein, Francine, Gross, Alden L., Bennett, David A., Walston, Jeremy D., Oh, Esther S., Abadir, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204157/
https://www.ncbi.nlm.nih.gov/pubmed/37221566
http://dx.doi.org/10.1186/s12979-023-00342-y