Fibroblast growth factor 21 attenuates ventilator-induced lung injury by inhibiting the NLRP3/caspase-1/GSDMD pyroptotic pathway

BACKGROUND: Ventilator-induced lung injury (VILI) is caused by overdistension of the alveoli by the repetitive recruitment and derecruitment of alveolar units. This study aims to investigate the potential role and mechanism of fibroblast growth factor 21 (FGF21), a metabolic regulator secreted by th...

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Detalles Bibliográficos
Autores principales: Ding, Peng, Yang, Rui, Li, Cheng, Fu, Hai-Long, Ren, Guang-Li, Wang, Pei, Zheng, Dong-Yu, Chen, Wei, Yang, Li-Ye, Mao, Yan-Fei, Yuan, Hong-Bin, Li, Yong-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204208/
https://www.ncbi.nlm.nih.gov/pubmed/37218012
http://dx.doi.org/10.1186/s13054-023-04488-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204208/
https://www.ncbi.nlm.nih.gov/pubmed/37218012
http://dx.doi.org/10.1186/s13054-023-04488-5

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