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Role of PARP inhibitors beyond BRCA mutation and platinum sensitivity in epithelial ovarian cancer: a meta-analysis of hazard ratios from randomized clinical trials

BACKGROUND: PARP inhibitors (PARPi) have a well-established role in platinum-sensitive ovarian cancer (PSOC), in BRCA mutant (BRCAm), and homologous recombination deficiency (HRD) population. However, their role in wild type and homologous recombination proficient population is still not clear. METH...

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Detalles Bibliográficos
Autores principales: Purwar, Roli, Ranjan, Rakesh, Pal, Manjusha, Upadhyay, Satyanshu K., Kumar, Tarun, Pandey, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204292/
https://www.ncbi.nlm.nih.gov/pubmed/37217940
http://dx.doi.org/10.1186/s12957-023-03027-4