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Graph construction method impacts variation representation and analyses in a bovine super-pangenome
BACKGROUND: Several models and algorithms have been proposed to build pangenomes from multiple input assemblies, but their impact on variant representation, and consequently downstream analyses, is largely unknown. RESULTS: We create multi-species super-pangenomes using pggb, cactus, and minigraph w...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204317/ https://www.ncbi.nlm.nih.gov/pubmed/37217946 http://dx.doi.org/10.1186/s13059-023-02969-y |