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Fatty acids metabolism affects the therapeutic effect of anti-PD-1/PD-L1 in tumor immune microenvironment in clear cell renal cell carcinoma

BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is a highly invasive and metastatic subtype of kidney malignancy and is correlated with metabolic reprogramming for adaptation to the tumor microenvironment comprising infiltrated immune cells and immunomodulatory molecules. The role of immune cell...

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Detalles Bibliográficos
Autores principales: Lin, Hansen, Fu, Liangmin, Li, Pengju, Zhu, Jiangquan, Xu, Quanhui, Wang, Yinghan, Mumin, Mukhtar Adan, Zhou, Xinwei, Chen, Yuhang, Shu, Guannan, Yao, Gaosheng, Chen, Minyu, Lu, Jun, Zhang, Lizhen, Liu, YuJun, Zhao, Yiqi, Bao, Jiahao, Chen, Wei, Luo, Junhang, Li, Xiaofei, Chen, Zhenhua, Cao, Jiazheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204332/
https://www.ncbi.nlm.nih.gov/pubmed/37221577
http://dx.doi.org/10.1186/s12967-023-04161-z