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Fatty acids metabolism affects the therapeutic effect of anti-PD-1/PD-L1 in tumor immune microenvironment in clear cell renal cell carcinoma
BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is a highly invasive and metastatic subtype of kidney malignancy and is correlated with metabolic reprogramming for adaptation to the tumor microenvironment comprising infiltrated immune cells and immunomodulatory molecules. The role of immune cell...
Autores principales: | Lin, Hansen, Fu, Liangmin, Li, Pengju, Zhu, Jiangquan, Xu, Quanhui, Wang, Yinghan, Mumin, Mukhtar Adan, Zhou, Xinwei, Chen, Yuhang, Shu, Guannan, Yao, Gaosheng, Chen, Minyu, Lu, Jun, Zhang, Lizhen, Liu, YuJun, Zhao, Yiqi, Bao, Jiahao, Chen, Wei, Luo, Junhang, Li, Xiaofei, Chen, Zhenhua, Cao, Jiazheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204332/ https://www.ncbi.nlm.nih.gov/pubmed/37221577 http://dx.doi.org/10.1186/s12967-023-04161-z |
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