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Attenuation of Dopaminergic Neurodegeneration in a C. elegans Parkinson’s Model through Regulation of Xanthine Dehydrogenase (XDH-1) Expression by the RNA Editase, ADR-2

Differential RNA editing by adenosine deaminases that act on RNA (ADARs) has been implicated in several neurological disorders, including Parkinson’s disease (PD). Here, we report results of a RNAi screen of genes differentially regulated in adr-2 mutants, normally encoding the only catalytically ac...

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Detalles Bibliográficos
Autores principales: Starr, Lindsey A., McKay, Luke E., Peter, Kylie N., Seyfarth, Lena M., Berkowitz, Laura A., Caldwell, Kim A., Caldwell, Guy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204437/
https://www.ncbi.nlm.nih.gov/pubmed/37218814
http://dx.doi.org/10.3390/jdb11020020