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Complement Activation by an Anti-Dengue/Zika Antibody with Impaired Fcγ Receptor Binding Provides Strong Efficacy and Abrogates Risk of Antibody-Dependent Enhancement

To combat infectious diseases, vaccines are considered the best prophylactic strategy for a wide range of the population, but even when vaccines are effective, the administration of therapeutic antibodies against viruses could provide further treatment options, particularly for vulnerable groups who...

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Detalles Bibliográficos
Autores principales: Sampei, Zenjiro, Koo, Christine Xing’er, Teo, Frannie Jiuyi, Toh, Ying Xiu, Fukuzawa, Taku, Gan, Siok Wan, Nambu, Takeru, Ho, Adrian, Honda, Kiyofumi, Igawa, Tomoyuki, Ahmed, Fariyal, Wang, Cheng-I, Fink, Katja, Nezu, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204484/
https://www.ncbi.nlm.nih.gov/pubmed/37218902
http://dx.doi.org/10.3390/antib12020036