Incubation Time Influences Organic Anion Transporter 1 Kinetics and Renal Clearance Predictions

Accurate predictions of drug uptake transporter involvement in renal excretion of xenobiotics require determination of in vitro transport kinetic parameters under initial-rate conditions. The purpose of the present study was to determine how changing the incubation time from initial rate to steady s...

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Detalles Bibliográficos
Autores principales: Buaben, Aaron O., Pelis, Ryan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204490/
https://www.ncbi.nlm.nih.gov/pubmed/37218810
http://dx.doi.org/10.3390/jox13020016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204490/
https://www.ncbi.nlm.nih.gov/pubmed/37218810
http://dx.doi.org/10.3390/jox13020016

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