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Incubation Time Influences Organic Anion Transporter 1 Kinetics and Renal Clearance Predictions
Accurate predictions of drug uptake transporter involvement in renal excretion of xenobiotics require determination of in vitro transport kinetic parameters under initial-rate conditions. The purpose of the present study was to determine how changing the incubation time from initial rate to steady s...
Autores principales: | Buaben, Aaron O., Pelis, Ryan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204490/ https://www.ncbi.nlm.nih.gov/pubmed/37218810 http://dx.doi.org/10.3390/jox13020016 |
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