An mRNA-based T-cell-inducing antigen strengthens COVID-19 vaccine against SARS-CoV-2 variants

Herd immunity achieved through mass vaccination is an effective approach to prevent contagious diseases. Nonetheless, emerging SARS-CoV-2 variants with frequent mutations largely evaded humoral immunity induced by Spike-based COVID-19 vaccines. Herein, we develop a lipid nanoparticle (LNP)-formulate...

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Detalles Bibliográficos
Autores principales: Tai, Wanbo, Feng, Shengyong, Chai, Benjie, Lu, Shuaiyao, Zhao, Guangyu, Chen, Dong, Yu, Wenhai, Ren, Liting, Shi, Huicheng, Lu, Jing, Cai, Zhuming, Pang, Mujia, Tan, Xu, Wang, Penghua, Lin, Jinzhong, Sun, Qiangming, Peng, Xiaozhong, Cheng, Gong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204679/
https://www.ncbi.nlm.nih.gov/pubmed/37221158
http://dx.doi.org/10.1038/s41467-023-38751-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204679/
https://www.ncbi.nlm.nih.gov/pubmed/37221158
http://dx.doi.org/10.1038/s41467-023-38751-8

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