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An mRNA-based T-cell-inducing antigen strengthens COVID-19 vaccine against SARS-CoV-2 variants
Herd immunity achieved through mass vaccination is an effective approach to prevent contagious diseases. Nonetheless, emerging SARS-CoV-2 variants with frequent mutations largely evaded humoral immunity induced by Spike-based COVID-19 vaccines. Herein, we develop a lipid nanoparticle (LNP)-formulate...
Autores principales: | Tai, Wanbo, Feng, Shengyong, Chai, Benjie, Lu, Shuaiyao, Zhao, Guangyu, Chen, Dong, Yu, Wenhai, Ren, Liting, Shi, Huicheng, Lu, Jing, Cai, Zhuming, Pang, Mujia, Tan, Xu, Wang, Penghua, Lin, Jinzhong, Sun, Qiangming, Peng, Xiaozhong, Cheng, Gong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204679/ https://www.ncbi.nlm.nih.gov/pubmed/37221158 http://dx.doi.org/10.1038/s41467-023-38751-8 |
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