Phase I trial outcome of amnion cell therapy in patients with ischemic stroke (I-ACT)

BACKGROUND: We proposed a Phase I dose escalation trial to assess the safety of allogeneic human amniotic epithelial cells (hAECs) in stroke patients with a view to informing the design for a Phase II trial. METHODS: The design is based on 3 + 3 dose escalation design with additional components for...

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Detalles Bibliográficos
Autores principales: Phan, Thanh G., Lim, Rebecca, Chan, Siow T., McDonald, Hannah, Gan, Poh-Yi, Zhang, Shenpeng R., Barreto Arce, Liz J., Vuong, Jason, Thirugnanachandran, Tharani, Clissold, Benjamin, Ly, John, Singhal, Shaloo, Hervet, Marie Veronic, Kim, Hyun Ah, Drummond, Grant R., Wallace, Euan M., Ma, Henry, Sobey, Christopher G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204798/
https://www.ncbi.nlm.nih.gov/pubmed/37229431
http://dx.doi.org/10.3389/fnins.2023.1153231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204798/
https://www.ncbi.nlm.nih.gov/pubmed/37229431
http://dx.doi.org/10.3389/fnins.2023.1153231

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