In-situ formed thermosensitive hydrogel amplifies statin-mediated immune checkpoint blockade for coordinated tumor chemo-immunotherapy

Small molecule drugs are the next-generation of immune checkpoint inhibitors (ICIs), but their in vivo therapeutic outcomes remain unsatisfactory for a long time. Herein, we proposed a combinatory regimen that delivered a small molecule ICI and an immunogenic cell death inducer in an in-situ formed...

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Detalles Bibliográficos
Autores principales: Liu, Zefan, Zhang, Yajun, Huang, Jinyu, Wang, Yan, Kang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204804/
https://www.ncbi.nlm.nih.gov/pubmed/37229252
http://dx.doi.org/10.3389/fphar.2023.1154392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204804/
https://www.ncbi.nlm.nih.gov/pubmed/37229252
http://dx.doi.org/10.3389/fphar.2023.1154392

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